Normal life of Wade Wilson(Ryan Reynolds) changes when an evil Scientist Ajax tortures and transforms him into Deadpool .He is left with super healing power and off course a great sense of humor .He starts looking for Ajax to get the cure and in his journey he also meets his "Robin to his Batman" Al, a blind women.At the end of the movie Wilson gets to know that there is no cure for this, he kills Ajax and he gets back to his ex-fiance Vanessa.
p.s- Usage of songs like Calendar Girls, Careless Whisper and etc adds more volume to the movie.(No puns intended)