On April world awake by hearing the news from scientists. They announced that they read 99.9% human genome sequence is over. A historiac step is scientific history. Now we can identify our identity. We can trace the disease which will came in our later lifetime! But there are so many negative side for this. Insurance companies will ask our DNA sequence during registration and they will reject the application if there is any chance to develop disease eventhough it is not appear at the time of application. The same will happen in recrutments. Young person who came to know that he will get cancer in his life then what will his mental situation? We can abort the featus if its DNA shows any defects. Thus a designed generation is possible. The positive side is to rectify the disease if we can find out in early stage. Gene theraphy is another advantage.