I have a Honda CBR 250 R. It is six years with this beast, still I did not come across with a more comfortable bike than this. More appropriately it can be your best bike for daily office ride and also have the capability to be your Sunday blaster for long high way rides.
It is very safe and feels highly comfortable at highways. As far as the mileage is concern, it is offering 25+km/lit. This bike is highly reliable as because it is equipped with wider tires. Road grip is also awesome even @110km/hr. Look wise there is no comparison of it in the 250 cc market.